Talk of the Nation

Doctors are running out of effective antibiotics, as bacteria evolve ways to evade one drug after another. Now DARPA has called for alternatives to conventional antibiotics. Nanotechnologist Chad Mirkin discusses one such weapon--tiny globs of DNA and RNA that can switch off the bugs' antibiotic resistance. Nanotechnologist Chad Mirkin discusses next-generation antibiotics that target a bacterium's DNA.

In his book Spontaneous Happiness, Dr. Andrew Weil writes of an 'integrative' approach to mental health, warding off mild and moderate depression with an anti-inflammatory diet, exercise and activities such as yoga and meditation, rather than antidepressants.

Pigeons may not be known for their flying prowess, but they are actually pretty good at maneuvering right angles. Andrew Biewener and colleagues at Harvard's Concord Field Station caught pigeons in a parking garage, made a flying course in the lab and filmed the birds with high speed cameras to see how pigeons make tight turns.

In her new book, The Heights: Anatomy of a Skyscraper, author Kate Ascher sheds light on the infrastructure and services that make life and work possible in a modern skyscraper. She examines everything that goes into designing, building and maintaining these towering buildings.

In a new book, Pulitzer Prize winning writer Richard Rhodes tells the behind-the-scenes story of movie star--and inventor-- Hedy Lamarr, "the most beautiful woman in the world." Lamarr invented "frequency hopping," a concept that's still used in today's wireless technology.

Nikky Finney has dreamed of being a poet since she was a teenager. She published her first book in 1985, and has taught writing for years at the university level.

Now, she's reached a pinnacle of success in the literary world: Her book, Head Off & Split received the National Book Award for poetry.

Richard Branson built a global business empire with the philosophy "have fun and the money will come."

As the founder of Virgin Group, he built a mail-order record company into a major record label and a chain of record stores, started an airline, created a space tourism company, and has been actively involved in humanitarian efforts.

Transcript

NEAL CONAN, HOST:

Forty years and a few days ago, an eight-and-a-half-minute song broke on to the record charts, soon drenched the radio and claimed a permanent place in the lives of millions.

(SOUNDBITE OF SONG, "AMERICAN PIE")

DON MCLEAN: (Singing) I can't remember if I cried when I read about his widowed bride. Something touched me deep inside the day the music died. So bye, bye, Miss American Pie. Drove my Chevy to the levee but the levee was dry.

Transcript

NEAL CONAN, HOST:

This is TALK OF THE NATION. I'm Neal Conan, in Washington. Wanted: a high-powered executive to run a nonprofit, far-flung public radio organization. Pluses include a trusted name, award-winning news and music programs, a growing audience and a talented staff. Minuses: some funding problems, a few self-inflicted controversies, the transition to digital media and staff who all think they're smarter than you.